Home > Giorgia Fattorini

Giorgia Fattorini Position: 2005-present: Assistant Professor, Department of Experimental and Clinical Medicine, Università Politecnica delle Marche, School of Medicine, Ancona, Italy. 2012-present: Researcher, Center for Neurobiology of Aging, INRCA IRCCS, Ancona, Italy.

C.V.

Education:
1997-2003: School of Medicine, University of Ancona, Ancona, Italy.
2003: M.D. Degree; Università Politecnica delle Marche, School of Medicine, Ancona, Italy.
Professional experience:
2000-2003: Undergraduate student; Department of Neuroscience, Section of Physiology
2003-2004: Resident: Department of Neuroscience, Section of Physiology, Università Politecnica delle Marche, School of Medicine, Ancona, Italy.
September 2009-March 2010: Post-doctoral fellow; Neurobiology Sector, SISSA, Trieste.

Publications:

Fattorini G, Melone M, Conti F. (2020) A Reappraisal of GAT-1 Localization in Neocortex. Frontiers in Cellular Neuroscience. doi: 10.3389/fncel.2020.00009

Fattorini G, Catalano M, Melone M, Serpe C, Bassi S, Limatola C, Conti, F. (2020) Microglial expression of GAT-1 in the cerebral cortex. Glia. 68: 3. doi: 10.1002/glia.23745

Fattorini G, Ripoli C, Cocco S, Spinelli M, Mattera A, Grassi C, Conti F (2019) Glutamate/GABA co-release selectively influences postsynaptic glutamate receptors in mouse cortical neurons. Neuropharmacology:107737. doi: 10.1016/j.neuropharm.2019.107737

Balietti M, Fattorini G, Pugliese A, Marcotulli D, Bragina L and Conti F (2018) Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins. Front. Aging Neurosci.10:91. doi: 10.3389/fnagi.2018.00091

Marcotulli D, Fattorini G, Bragina L, Perugini J, Conti F (2017) Levetiracetam Affects Differentially Presynaptic Proteins in Rat Cerebral Cortex. Front. Cell. Neurosci. 11:389. doi: 10.3389/fncel.2017.00389

Fattorini G, Ciriachi C, Conti F (2017) Few, Activity-Dependent, and Ubiquitous VGLUT1/VGAT Terminals in Rat and Mouse Brain. Frontiers in Cellular Neuroscience 11:229. doi: 10.3389/fncel.2017.00229.

Fattorini G, Melone M, Sánchez-Gómez MV, Arellano RO, Bassi S, Matute C, Conti F (2017). GAT-1 mediated GABA uptake in rat oligodendrocytes. Glia 65:514-522. doi: 10.1002/glia.23108

Fattorini G, Antonucci F, Menna E, Matteoli M, Conti F (2015) Co‐expression of VGLUT1 and VGAT sustains glutamate and GABA co‐release and is regulated by activity in cortical neurons. Journal of Cell Science 128:1669-1673 doi:10.1242/jcs.164210.

Cristóvão-Ferreira S, Navarro G, Brugarolas M, Pérez-Capote K, Vaz SH, Fattorini G, Conti F, Lluis C, Ribeiro JA, McCormick PJ, Casadó V, Franco R, Sebastião AM (2013) A₁R-A_2AR heteromers coupled to G_s and G_i/0 proteins modulate GABA transport into astrocytes. Purinergic Signalling 9:433-449. doi:10.1007/s11302-013-9364-5.

Caiati MD, Safiulina VF, Fattorini G, Sivakumaran S, Legname G, Cherubini E (2013) PrP^C controls via protein kinase A the direction of synaptic plasticity in the immature hippocampus. Journal of Neuroscience 33:2973–2983.

Bragina L, Fattorini G, Giovedì S, Bosco F, Benfenati F, Conti F (2013). Heterogeneity of presynaptic proteins: do not forget isoforms. Frontiers in Cellular Neuroscience 7:8. doi: 10.3389/fncel.2013.00008.

Bragina L, Fattorini G, Giovedí S, Melone M, Bosco F, Benfenati F, Conti F (2012) Analysis of synaptotagmin, SV2, and Rab3 expression in cortical glutamatergic and GABAergic axon terminals. Frontiers in Cellular Neuroscience 5:32.doi:10.3389/fncel.2011.00032.

Conti F, Melone M, Fattorini G, Bragina L, Ciappelloni S (2011) A role for GAT-1 in presynaptic GABA homeostasis? Frontiers in Cellular Neuroscience 5:2. doi: 10.3389/fncel.2011.00002

Fattorini G, Verderio C, Melone M, Giovedì S, Benfenati F, Matteoli M , Conti  F (2009) VGLUT1 and VGAT are sorted to the same populations of synaptic vesicles in subsets of cortical axon terminals. Journal of Neurochemistry 110:1538-1546

Fattorini G, Bragina L, Candiracci C, Melone M, Cozzi A, Pellegrini-Giampietro DE, Conti F (2009) Acute phencyclidine administration reduces extracellular glutamate levels and the expression of synaptophysin and SNAP-25 in rat frontal cortex. Schizophrenia Research 108:288-289.

Fattorini G, Melone M, Bragina L, Candiracci C, Cozzi A, Pellegrini-Giampietro DE, Torres-Ramos M, Pérez-Samartín A, Matute C, Conti F (2008) GLT-1 expression and Glu uptake in rat cerebral cortex are increased by phencyclidine. Glia 56: 1320-1327.

Bragina L, Melone M, Fattorini G, Conti F (2007) Clozapine up-regulates the expression of the vesicular GABA transporter (VGAT) in rat frontal cortex. Molecular Psychiatry 12: 612-613.

Bragina L, Melone M, Fattorini G, Torres-Ramos M, Vallejo-Illarramendi A, Matute C, Conti F (2006) GLT-1 down-regulation induced by clozapine in rat frontal cortex is associated with synaptophysin up-regulation. Journal of Neurochemistry 99:134-141.

Safiulina VF, Fattorini G, Conti F, Cherubini E (2006) GABAergic signaling at mossy fiber synapses in neonatal rat hippocampus. Journal of Neuroscience 26:597-608.

Melone M, Barbaresi P, Fattorini G, Conti F (2005) Neuronal localization of the GABA transporter GAT-3 in human cerebral cortex: a procedural artifact? Journal of Chemical Neuroanatomy 30:45-54.

Conti F, Candiracci C, Fattorini G (2005) Heterogeneity of axon terminals expressing VGLUT1 in the cerebral neocortex. Archives Italienne de Biologie 143:127-132.